Academic in Focus: Dr. Irshad Ahmad – Bridging the gap between inorganic, organic, analytical and bioorganic chemistry

AURAK’s Associate Professor of Chemistry – Dr. Irshad Ahmad – has over 20 years of research experience in the field of chemistry and over ten years’ experience in teaching within an American style university.  His credentials in research range from Canada where he worked as a visiting professor at the University of Toronto to his time in India at the Jawaharlal Nehru Centre for Advanced Scientific Research in the International Centre for Material Science and Sheikh Saqr Laboratory (SSL).

In addition to being a Visiting Fellow of the Sheikh Saqr Laboratory, Dr. Ishad has worked in a number of prestigious institutions. During his time at the Department of Chemistry and Biochemistry, Stephenson Life Science Research Center in the University of Oklahoma, he was involved in a project sponsored by  US Department of Energy development.  This project involved the development of strategies for environmentally friendly reactions for the production of value-added chemicals from biomass-derived diols and polyols.  Dr. Irshad also designed and synthesized the novel, ultra-fast Ruthenium based metathesis catalyst for the production of alternating copolymers as part of a sponsored project by the German Research Foundation (DFG) at the Leibniz Institute for Surface Modification, Leipzig, Germany.   During his time at the Central Salt and Marine Chemical Research Institute and Bhavnagar University, Dr. Irshad’s early career at the Central Salt and Marine Chemical Research Institute and Bhavnagar University where he studied towards his doctorate involved systematically investigating asymmetric catalytic transformations in organometallic chemistry in the stereo-selective synthesis of chiral drug intermediates.  This project was sponsored by the Government of India’s Department of Science and Technology (DST) and, Council of Scientific and Industrial Research (CSIR).  Throughout his career, Dr. Irshad has been recognized for his contribution to research and has been the recipient of many prestigious awards such as the European fellowship from the Netherlands Organization for Scientific Research.  He also joined the Van’t Hoff Institute for Molecular Sciences at the University of Amsterdam as a NWO Rubicon fellow, where he acquired expertise in the field of supramolecular chemistry.  In addition to this, Dr. Irshad was an invited scientist at the Korean Research Institute of Chemical Technology (KRICT), Daejon, South Korea and contributed to the development of nanomaterials, in which the carbon and silica based nanomaterials were characterized by analytical techniques.

Dr. Irshad has strong working knowledge of the upscaling industrial chemical processes which he gained during his time at the Indian Pharmaceutical Combine Association Limited (IPCa). He also has worked as Research and Development Chemist, acquiring significant pharmaceutical industrial experience in the development of cardio-selective beta-blockers, an antihyperglycemic drug used in the management of type 2 diabetes, and in purification techniques for nonsteroidal anti-inflammatory drug molecules.

Dr. Irshad’s specialized work in chemistry has bridged the traditional disciplines of inorganic, organic, analytical and bioorganic chemistry. He contributed to the development of a US and European patent for green and clean technology development and he is widely published in international peer-reviewed journals and is invited to present at many at scientific conferences worldwide.

Selected publications:

  1. (a) Shagufta, and Ahmad, I., Transition metal complexes as proteasome inhibitors for cancer treatment. Inorganica Chimica Acta. 2020, 506, 119521. (b) Shagufta, Ahmad, I., Mathew, S., and Rahman, S., Recent progress in selective estrogen receptor downregulators (SERDs) for the treatment of breast cancer. RSC Medicinal Chemistry. 2020, 11, 438-454.
  2. Ahmad, I., Shagufta, and AlMallah, A. R., Advances in Asymmetric Oxidative Kinetic Resolution of Racemic Secondary Alcohols Catalyzed by Chiral Manganese (III) Salen Complexes. 2017, 2:12, 798-810.
  3. Ahmad, I., Shagufta, Recent developments in steroidal and nonsteroidal aromatase inhibitors for the chemoprevention of estrogen-dependent breast cancer. European Journal of Medicinal Chemistry. 2015, 102:375-386.
  4. Kumar, R., Raut, D., Ahmad,, Ramamurty, U., Maji, T. K., and Rao, C. N. R., Functionality preservation with enhanced mechanical integrity in the nanocomposites of the metal–organic framework, ZIF-8, with BN nanosheets. Materials Horizons.2014, 1:513-517.
  5. Ahmad, I., Chapman, G., and Nicholas, K. M., Sulfite-Driven, Oxorhenium-Catalyzed Deoxydehydration of Glycols. Organometallics. 2011, 30:10, 2810-2818.

Research Interests:

Dr. Irshad’s research interests include mainly the development of innovative strategies for the design and synthesis of organometallic complexes, functional solid-state 2D nanomaterials, pharmaceutically active molecules, and environmentally benign catalysts. These strategies address some of the most challenging and enduring societal necessities, such as clean energy alternatives and the protection of the environment: hydrogen production, CO2 capture and conversion to reduce the greenhouse effect, catalytic transformation of biomass-derived diols/polyols to biofuel, FLPs chemistry for metal-free catalytic hydrogenations of alkenes, and wastewater treatment. In addition, his research has implication for drug discovery paradigms: for example, advancing the understanding of the structure-activity relationship of designed and synthesized bioactive molecules with the prime focus on anticancer activity.

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Last updated: Feb 15, 2021 @ 2:51 pm

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